What Is Intravenous Immunoglobulin IVIG Treatment?

 

 

What Is Intravenous Immunoglobin IVIG Treatment?

Intravenous Immunoglobulin (IVIG) is a blood product prepared from the serum of between 1000 and 15000 donors per batch.

IVIG intravenous treatment occurs when the patient is given IVIG to treat a serious condition or disease.  Immunoglobin IVIG is the treatment of choice for patients with antibody deficiencies.

Is Intravenous Immunoglobin IVIG Treatment Effective?

Intravenous Immunoglobin IVIG treatment has shown effectiveness for numerous autoimmune diseases.

The Food and Drug Administration (FDA)-approved indications for immune globulin therapy are limited, but a large number of diseases, especially those seen by neurologists, have shown potentially beneficial responses to IVIG.

Based on controlled clinical trials IVIG is now recognized as first-line therapy in patients with Guillain–Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and multifocal motor neuropathy (MMN).

Intravenous Immunoglobulin is an effective rescue therapy in some patients with worsening myasthenia gravis (MG) and beneficial as second-line therapy in patients with dermatomyositis and stiff-person syndrome.

Despite Intravenous Immunoglobulin IVIG widespread use and broad efficacy, the mechanisms that confer the anti-inflammatory or immunomodulating activity in autoimmune disease conditions are poorly understood.

In a large number of case series but not controlled studies, IVIG is also promising in treating various neuroinflammatory, painful, or even neurodegenerative disorders.

Is Intravenous Immunoglobin IVIG Treatment Expensive?

The rarity and demand for Intravenous Immunoglobin IVIG cause the medication to be expensive. As a result of IVIG cost and usage, IVIG treatment is not always approved by insurance carriers.

 

I hope this HypoGal Blog, What Is Intravenous Immunoglobulin IVIG Treatment? has been insightful.

 

Resources: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1809480/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720677/

 

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